Protein name:
Neprilysin ;
Alternative:
Enkephalinase ;Atriopeptidase ;Skin fibroblast elastase (SFE) ;Neutral endopeptidase 24.11 (NEP;Neutral endopeptidase) ;
CD:
CD10 ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (By similarity). Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
Subcellular Location:
Cell membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MGRSESQMDI | TDINAPKPKK | KQRWTPLEIS | LSVLVLLLTI | IAVTMIALYA |
100:
TYDDGICKSS | DCIKSAARLI | QNMDASVEPC | TDFFKYACGG | WLKRNVIPET |
150:
SSRYSNFDIL | RDELEVILKD | VLQEPKTEDI | VAVQKAKTLY | RSCINESAID |
200:
SRGGQPLLKL | LPDIYGWPVA | SDNWDQTYGT | SWTAEKSIAQ | LNSKYGKKVL |
250:
INFFVGTDDK | NSTQHIIHFD | QPRLGLPSRD | YYECTGIYKE | ACTAYVDFMI |
300:
SVARLIRQEQ | SLPIDENQLS | LEMNKVMELE | KEIANATTKP | EDRNDPMLLY |
350:
NKMTLAKLQN | NFSLEVNGKS | FSWSNFTNEI | MSTVNINIQN | EEEVVVYAPE |
400:
YLTKLKPILT | KYSPRDLQNL | MSWRFIMDLV | SSLSRNYKES | RNAFRKALYG |
450:
TTSETATWRR | CANYVNGNME | NAVGRLYVEA | AFAGESKHVV | EDLIAQIREV |
500:
FIQTLDDLTW | MDAETKKKAE | EKALAIKERI | GYPDDIISNE | NKLNNEYLEL |
550:
NYREDEYFEN | IIQNLKFSQS | KQLKKLREKV | DKDEWISGAA | VVNAFYSSGR |
600:
NQIVFPAGIL | QPPFFSAQQS | NSLNYGGIGM | VIGHEITHGF | DDNGRNFNKD |
650:
GDLVDWWTQQ | SANNFKDQSQ | CMVYQYGNFS | WDLAGGQHLN | GINTLGENIA |
700:
DNGGIGQAYR | AYQNYVKKNG | EEKLLPGLDL | NHKQLFFLNF | AQVWCGTYRP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Pig
Rabbit
Mouse
ELISA Kit for Mouse Neprilysin
ELISA Kit for Mouse Neprilysin
ELISA Kit for Mouse Neprilysin
ELISA Kit for Mouse Neprilysin
ELISA Kit for Mouse Neprilysin
CLIA Kit for Mouse Neprilysin
CLIA Kit for Mouse Neprilysin
CLIA Kit for Mouse Neprilysin
CLIA Kit for Mouse Neprilysin
CLIA Kit for Mouse Neprilysin
Polyclonal Antibody for Mouse Neprilysin
Polyclonal Antibody for Mouse Neprilysin
Polyclonal Antibody for Mouse Neprilysin
Polyclonal Antibody for Mouse Neprilysin
Polyclonal Antibody for Mouse Neprilysin
Monoclonal Antibody for Mouse Neprilysin
Monoclonal Antibody for Mouse Neprilysin
Monoclonal Antibody for Mouse Neprilysin
Monoclonal Antibody for Mouse Neprilysin
Monoclonal Antibody for Mouse Neprilysin
Protein for Mouse Neprilysin
Protein for Mouse Neprilysin
Protein for Mouse Neprilysin
Protein for Mouse Neprilysin
Protein for Mouse Neprilysin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
BALB/c .
2.
"The transcriptional landscape of the mammalian genome."
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Epididymis .
tissue :
Testis .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
strain :
FVB/N .
tissue :
Embryonic germ cell .
tissue :
Mammary tumor .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 473-479;IDENTIFICATION BY MASS SPECTROMETRY
strain :
OF1 .
tissue :
Hippocampus .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-145; ASN-285; ASN-311 AND ASN-317
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION AS SKIN FIBROBLAST ELASTASE;FUNCTION